CAS OpenIR  > 中科院上海应用物理研究所2011-2020年
DNA Origami Radiometers for Measuring Ultraviolet Exposure
Fang, WN; Xie, M; Hou, XL; Liu, XG; Zuo, XL; Chao, J; Wang, LH; Fan, CH; Liu, HJ; Wang, LH
2020
Source PublicationJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
ISSN0002-7863
Volume142Issue:19Pages:8782-8789
Subtype期刊论文
AbstractUltraviolet (UV) light has long been known to damage nucleic acids. In this work, a DNA origami radiometer has been developed for measuring UV exposure by monitoring the morphological evolution of DNA origami nanostructures. Unlike linear DNA strands that tend to be degraded into small segments upon UV exposure, the structural complexity and interstrand connectivity of DNA origami remarkably alter the pathway of UV-induced DNA damage. A general pathway of expansion, distortion, and final disintegration is observed for DNA origami regardless of their shape and size; however the deformation kinetics is positively correlated with the number of nicks in the nanostructure. This structural continuity-dependent deformation can be translated into a DNA-based radiometer for measuring UV dose in the environment.
KeywordUV NANOSTRUCTURES DAMAGE RADIATION STABILITY CANCER
DOI10.1021/jacs.0c01254
Indexed BySCI
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/32809
Collection中科院上海应用物理研究所2011-2020年
Affiliation1.Tongji Univ, Sch Chem Sci & Engn, Key Lab Adv Civil Engn Mat,Minist Educ, Shanghai Res Inst Intelligent Autonomous Syst, Shanghai 200092, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China
3.Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China
4.Shanghai Jiao Tong Univ, Frontiers Sci Ctr Transformat Mol, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China
5.Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Inst Mol Med,Shanghai Key Lab Nucle Acids Chem &, Shanghai 200240, Peoples R China
6.Nanjing Univ Posts & Telecommun, Inst Adv Mat IAM, Key Lab Organ Elect & Informat Displays KLOEID, Nanjing 210046, Peoples R China
7.Nanjing Univ Posts & Telecommun, Sch Mat Sci & Engn, Nanjing 210046, Peoples R China
Recommended Citation
GB/T 7714
Fang, WN,Xie, M,Hou, XL,et al. DNA Origami Radiometers for Measuring Ultraviolet Exposure[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2020,142(19):8782-8789.
APA Fang, WN.,Xie, M.,Hou, XL.,Liu, XG.,Zuo, XL.,...&Wang, LH.(2020).DNA Origami Radiometers for Measuring Ultraviolet Exposure.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,142(19),8782-8789.
MLA Fang, WN,et al."DNA Origami Radiometers for Measuring Ultraviolet Exposure".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 142.19(2020):8782-8789.
Files in This Item:
File Name/Size DocType Version Access License
DNA Origami Radiomet(5297KB)期刊论文出版稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Fang, WN]'s Articles
[Xie, M]'s Articles
[Hou, XL]'s Articles
Baidu academic
Similar articles in Baidu academic
[Fang, WN]'s Articles
[Xie, M]'s Articles
[Hou, XL]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Fang, WN]'s Articles
[Xie, M]'s Articles
[Hou, XL]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: DNA Origami Radiometers for Measuring Ultraviolet Exposure.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.