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Dosimetric characterization of model Cs-1 Rev2 cesium-131 brachytherapy source in water phantoms and human tissues with MCNP5 Monte Carlo simulation
Wang, JH(王建华); Zhang, HL; Wang, JH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2008
Source PublicationMEDICAL PHYSICS
ISSN0094-2405
Volume35Issue:4Pages:1571
AbstractA recently developed alternative brachytherapy seed, Cs-1 Rev2 cesium-131, has begun to be used in clinical practice. The dosimetric characteristics of this source in various media, particularly in human tissues, have not been fully evaluated. The aim of this study was to calculate the dosimetric parameters for the Cs-1 Rev2 cesium-131 seed following the recommendations of the AAPM TG-43U1 report [Rivard , Med. Phys. 31, 633-674 (2004)] for new sources in brachytherapy applications. Dose rate constants, radial dose functions, and anisotropy functions of the source in water, Virtual Water (TM), and relevant human soft tissues were calculated using MCNP5 Monte Carlo simulations following the TG-43U1 formalism. The results yielded dose rate constants of 1.048, 1.024, 1.041, and 1.044 cGy h(-1) U-1 in water, Virtual Water (TM), muscle, and prostate tissue, respectively. The conversion factor for this new source between water and Virtual Water (TM) was 1.02, between muscle and water was 1.006, and between prostate and water was 1.004. The authors' calculation of anisotropy functions in a Virtual Water (TM) phantom agreed closely with Murphy's measurements [Murphy , Med. Phys. 31, 1529-1538 (2004)]. Our calculations of the radial dose function in water and Virtual Water (TM) have good agreement with those in previous experimental and Monte Carlo studies. The TG-43U1 parameters for clinical applications in water, muscle, and prostate tissue are presented in this work. (c) 2008 American Association of Physicists in Medicine.
Subject AreaPhysics
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000254510700045
Citation statistics
Cited Times:12[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/7699
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorWang, JH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Wang, JH,Zhang, HL,Wang, JH . Dosimetric characterization of model Cs-1 Rev2 cesium-131 brachytherapy source in water phantoms and human tissues with MCNP5 Monte Carlo simulation[J]. MEDICAL PHYSICS,2008,35(4):1571.
APA Wang, JH,Zhang, HL,&Wang, JH .(2008).Dosimetric characterization of model Cs-1 Rev2 cesium-131 brachytherapy source in water phantoms and human tissues with MCNP5 Monte Carlo simulation.MEDICAL PHYSICS,35(4),1571.
MLA Wang, JH,et al."Dosimetric characterization of model Cs-1 Rev2 cesium-131 brachytherapy source in water phantoms and human tissues with MCNP5 Monte Carlo simulation".MEDICAL PHYSICS 35.4(2008):1571.
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