CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Gold nanoparticle-based optical probes for target-responsive DNA structures
Wang, LH(王丽华); Zhang, J; Wang, X; Huang, Q(黄庆); Pan, D; Song, SP(宋世平); Fan, CH(樊春海); Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2008
Source PublicationGOLD BULLETIN
ISSN0017-1557
Volume41Issue:1Pages:37
AbstractIn this work, we report the use of unmodified gold nanoparticles (AuNPs) as an optical probe for the detection of target-responsive structural variations of DNA. By employing two DNA structures, i.e., a pH-responsive i-motif oligonucleotide and a mercury-specific oligonucleotide (MSO), we demonstrated that AuNPs could selectively distinguish target-free and target-bound oligonucleotides via the characteristic surface plasmon resonance-associated red-to-blue color change. Based on these observations, we developed a convenient "mix-and-detect" approach that could selectively detect environmentally toxic mercury ions.
Subject AreaNuclear Science & Technology ; Physics
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000254976500005
Citation statistics
Cited Times:52[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/7740
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorFan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Wang, LH,Zhang, J,Wang, X,et al. Gold nanoparticle-based optical probes for target-responsive DNA structures[J]. GOLD BULLETIN,2008,41(1):37.
APA Wang, LH.,Zhang, J.,Wang, X.,Huang, Q.,Pan, D.,...&Fan, CH .(2008).Gold nanoparticle-based optical probes for target-responsive DNA structures.GOLD BULLETIN,41(1),37.
MLA Wang, LH,et al."Gold nanoparticle-based optical probes for target-responsive DNA structures".GOLD BULLETIN 41.1(2008):37.
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