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| Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing | |
| Yang, XM(杨小敏）; Liu, Q; Chen, XL; Yu, F; Zhu, ZY（朱智勇）; Zhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China | |
| 2008 | |
| Source Publication | CARBOHYDRATE POLYMERS
 |
| ISSN | 0144-8617 |
| Volume | 73Issue:3Pages:401 |
| Abstract | gamma-Irradiation combined with freeze-thawing, i.e. irradiation followed by freeze-thawing and freezc-thawing followed by irradiation, was applied to prepare poly(vinyl alcohol) (PVA)/water soluble chitosan (ws-chitosan) hydrogels for wound dressing. The properties of these hydrogels were investigated and compared to those prepared by freeze-thawing and by irradiation, respectively. Hydrogels made by irradiation followed by freeze-thawing show larger swelling capacity and mechanical strength, higher thermal stability, lower water evaporation rate, and are less turbid than those made by pure freeze-thawing and freeze-thawing followed by irradiation. Hydrogels made by irradiation alone cannot be used as wound dressing due to their poor mechanical strength. SEM results show that the final structure of hydrogels made by combined irradiation and freeze-thawing is mainly determined by the first processing step. It is found that the appropriate amount of ws-chitosan can endow hydrogels with large swelling capacity and mechanical strength. The presence of ws-chitosan provides the hydrogels with good antibacterial activity against Escherichia coli (E. coli). (C) 2008 Elsevier Ltd. All rights reserved. |
| Subject Area | Physics |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000256500200005 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/7755 |
| Collection | 中科院上海应用物理研究所2004-2010年 |
| Corresponding Author | Zhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China |
| Recommended Citation GB/T 7714 | Yang, XM,Liu, Q,Chen, XL,et al. Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing[J]. CARBOHYDRATE POLYMERS,2008,73(3):401. |
| APA | Yang, XM,Liu, Q,Chen, XL,Yu, F,Zhu, ZY,&Zhu, ZY .(2008).Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing.CARBOHYDRATE POLYMERS,73(3),401. |
| MLA | Yang, XM,et al."Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing".CARBOHYDRATE POLYMERS 73.3(2008):401. |
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