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Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing
Yang, XM(杨小敏); Liu, Q; Chen, XL; Yu, F; Zhu, ZY(朱智勇); Zhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China
2008
Source PublicationCARBOHYDRATE POLYMERS
ISSN0144-8617
Volume73Issue:3Pages:401
Abstractgamma-Irradiation combined with freeze-thawing, i.e. irradiation followed by freeze-thawing and freezc-thawing followed by irradiation, was applied to prepare poly(vinyl alcohol) (PVA)/water soluble chitosan (ws-chitosan) hydrogels for wound dressing. The properties of these hydrogels were investigated and compared to those prepared by freeze-thawing and by irradiation, respectively. Hydrogels made by irradiation followed by freeze-thawing show larger swelling capacity and mechanical strength, higher thermal stability, lower water evaporation rate, and are less turbid than those made by pure freeze-thawing and freeze-thawing followed by irradiation. Hydrogels made by irradiation alone cannot be used as wound dressing due to their poor mechanical strength. SEM results show that the final structure of hydrogels made by combined irradiation and freeze-thawing is mainly determined by the first processing step. It is found that the appropriate amount of ws-chitosan can endow hydrogels with large swelling capacity and mechanical strength. The presence of ws-chitosan provides the hydrogels with good antibacterial activity against Escherichia coli (E. coli). (C) 2008 Elsevier Ltd. All rights reserved.
Subject AreaPhysics
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000256500200005
Citation statistics
Cited Times:102[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/7755
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorZhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Yang, XM,Liu, Q,Chen, XL,et al. Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing[J]. CARBOHYDRATE POLYMERS,2008,73(3):401.
APA Yang, XM,Liu, Q,Chen, XL,Yu, F,Zhu, ZY,&Zhu, ZY .(2008).Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing.CARBOHYDRATE POLYMERS,73(3),401.
MLA Yang, XM,et al."Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing".CARBOHYDRATE POLYMERS 73.3(2008):401.
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