CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Double roles of hydroxycinnamic acid derivatives in protection against lysozyme oxidation
Zhu, HP; Chen, SM; Hao, SM; Zhang, ZX; Wang, WF(王文锋); Yao, SD(姚思德); Wang, WF (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2006
Source PublicationBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
ISSN0304-4165
Volume1760Issue:12Pages:1810
AbstractOxidative damage to protein has been implicated in a number of diseases. Much interest has been focused on preventing oxidative damage to protein. Here we showed that hydroxycinnamic acid derivatives (HCA) were able to inhibit the cross-linking of protein induced by riboflavin-mediated photooxidation. HCA were also found to strongly protect lysozyme from gamma rays irradiation. The antioxidative properties of HCA were further studied by laser flash photolysis. Mechanism of antioxidant activities of HCA on lysozyme oxidation was discussed. HCA were found to protect protein against oxidation by scavenging oxidizing species and repairing the damaged protein. (c) 2006 Elsevier B.V. All rights reserved.
KeywordHydroxycinnamic Acid Derivatives Protein Oxidation Antioxidant Protection Mechanism
Subject AreaPhysics
Indexed Bysci
Language英语
Funding Project应物所项目组
WOS IDWOS:000242459500008
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8042
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorWang, WF (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Zhu, HP,Chen, SM,Hao, SM,et al. Double roles of hydroxycinnamic acid derivatives in protection against lysozyme oxidation[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2006,1760(12):1810.
APA Zhu, HP.,Chen, SM.,Hao, SM.,Zhang, ZX.,Wang, WF.,...&Wang, WF .(2006).Double roles of hydroxycinnamic acid derivatives in protection against lysozyme oxidation.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1760(12),1810.
MLA Zhu, HP,et al."Double roles of hydroxycinnamic acid derivatives in protection against lysozyme oxidation".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1760.12(2006):1810.
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