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Fabricating protein nanopatterns on a single DNA molecule with Dip-pen nanolithography | |
Li, B(李宾); Zhang, Y(张益); Hu, J(胡钧); Li, MQ(李铭乾); Li, MQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China | |
2005 | |
Source Publication | ULTRAMICROSCOPY
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ISSN | 0304-3991 |
Volume | 105Issue:40547Pages:312 |
Abstract | Positioning proteins onto single DNA molecules is of great importance for basic research in biology as well as direct applications in nanotechnology. Herein, the generality of an atomic force microscopy (AFM)-based Dip-pen nanolithography (DPN) approach is explored and extended to fabricate protein nanopatterns along a single DNA molecule. Important procedures are presented, including a modified molecular combing method for DNA stretching and DPN for depositing protein "ink". This approach is able to check resulting pattern by AFM at real time and in situ. (c) 2005 Elsevier B.V. All rights reserved. |
Keyword | Atomic Force Microscopy (Afm) Dip-pen Nanolithography (Dpn) Single Dna Molecules Protein Nanoarray |
Subject Area | Engineering |
Indexed By | sci |
Language | 英语 |
Funding Project | 应物所项目组 |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/8056 |
Collection | 中科院上海应用物理研究所2004-2010年 |
Corresponding Author | Li, MQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China |
Recommended Citation GB/T 7714 | Li, B,Zhang, Y,Hu, J,et al. Fabricating protein nanopatterns on a single DNA molecule with Dip-pen nanolithography[J]. ULTRAMICROSCOPY,2005,105(40547):312. |
APA | Li, B,Zhang, Y,Hu, J,Li, MQ,&Li, MQ .(2005).Fabricating protein nanopatterns on a single DNA molecule with Dip-pen nanolithography.ULTRAMICROSCOPY,105(40547),312. |
MLA | Li, B,et al."Fabricating protein nanopatterns on a single DNA molecule with Dip-pen nanolithography".ULTRAMICROSCOPY 105.40547(2005):312. |
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