CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation
Li, B(李宾); Zhang, Y(张益); Yan, SH; Lu, JH; Ye, M(叶鸣); Li, MQ(李明乾); Hu, J(胡钧); Zhang, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2007
Source PublicationJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
ISSN0002-7863
Volume129Issue:21Pages:6668
AbstractControlling chemical and biochemical reactions on nanoscale at the single-molecule level is of great interest due to its possibility for exploring new phenomena and/or unraveling novel mechanisms that are inaccessible for traditional bulk systems. In this paper, we report how DNase I, a well-known and widely used nonspecific endonuclease, digested DNA at controlled sites by using an approach termed combined-dynamic dip-pen nanolithography (CDDPN). High efficient digestion has been realized even under an ambient condition on the surfaces. We attribute this phenomenon to a high effective concentration of DNase I when confined in the nanospots.
Subject AreaChemistry ; Nuclear Science & Technology
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000246686700003
Citation statistics
Cited Times:27[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8162
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorZhang, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Li, B,Zhang, Y,Yan, SH,et al. Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2007,129(21):6668.
APA Li, B.,Zhang, Y.,Yan, SH.,Lu, JH.,Ye, M.,...&Zhang, Y .(2007).Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,129(21),6668.
MLA Li, B,et al."Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 129.21(2007):6668.
Files in This Item: Download All
File Name/Size DocType Version Access License
Positioning scission(145KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li, B(李宾)]'s Articles
[Zhang, Y(张益)]'s Articles
[Yan, SH]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li, B(李宾)]'s Articles
[Zhang, Y(张益)]'s Articles
[Yan, SH]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li, B(李宾)]'s Articles
[Zhang, Y(张益)]'s Articles
[Yan, SH]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.