CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Synchrotron refractive-index microradiography of human liver cancer tissue
Tong, YP(童永彭); Zhang, GL(张桂林); Li, Y(李燕); Hwu, Y; Tsai, W; Ho, JEJ; Margaritondo, G; Yuan, DA; Zhang, GL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2005
Source PublicationCHINESE SCIENCE BULLETIN
ISSN1001-6538
Volume50Issue:22Pages:2657
AbstractThree human liver tissue samples (similar to 5 mm x 40 mm x 20 mm) were excised from a cancer patient's liver during surgery. The microradiology analysis was performed with a non-standard approach on a synchrotron. High-resolution refractive-index edge-enhanced microradiographs that cover a larger volume of the liver tissue sample were obtained. The cancer tissue and normal tissue could be clearly identified and distinguished based on their different textures. Furthermore, new blood vessel hyperplasia was found near the cancer area. Blood vessels with a diameter smaller than 20 pm could be identified. These findings were fully consistent with the histopathological examination of the same area. Microradiographs of the newly formed blood vessels at different angles were also obtained. This result shows that it is possible to further develop this approach into a technique of microradiographic imaging for clinic diagnosis of liver cancer at the early stage.
KeywordSynchrotron Microradiology Liver Cancer Histopathology
Subject AreaEngineering
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000234866000021
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8210
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorZhang, GL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Tong, YP,Zhang, GL,Li, Y,et al. Synchrotron refractive-index microradiography of human liver cancer tissue[J]. CHINESE SCIENCE BULLETIN,2005,50(22):2657.
APA Tong, YP.,Zhang, GL.,Li, Y.,Hwu, Y.,Tsai, W.,...&Zhang, GL .(2005).Synchrotron refractive-index microradiography of human liver cancer tissue.CHINESE SCIENCE BULLETIN,50(22),2657.
MLA Tong, YP,et al."Synchrotron refractive-index microradiography of human liver cancer tissue".CHINESE SCIENCE BULLETIN 50.22(2005):2657.
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