CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Zinc distribution in mouse brain by SRXRF
Zhang, YX(张元勋); Zhang, YP(张勇平); Li, DL; Zhang, GL(张桂林); Long, JG(龙家丽); Shen, H; Huang, YY; He, W; Zhang, YX (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
2006
Source PublicationJOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
ISSN0236-5731
Volume269Issue:1Pages:235
AbstractIn order to explore the interaction between the expression of ZnT3 (Zinc Transporter 3) mRNA (Messenger Ribonucleic Acid) and the concentration of elemental zinc in mouse brain, zinc distribution in brain was determined by synchrotron radiation X-ray fluorescence (SRXRF) technique and a ZnT3 mRNA expression in tissue was examined by the reverse-transcriptase polymerase chain reaction (RT-PCR) method.The results show that the zinc concentration is not evenly distributed in brain slices. Its concentrations in cerebral cortex and hippocampus are nearly 5-10 times higher than those in other positions. A corresponding relation is that ZnT3 mRNA in cerebral cortex, hippocampus and testis has higher abundant degree, but it is not examined out in other tissues. Furthermore, the results promote that ZnT3 facilitates the accumulation of zinc in synaptic vesicles and may play an important role in structuring of vesicular zinc pool.
Subject AreaPhysics
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000239298600036
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8241
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorZhang, YX (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
Recommended Citation
GB/T 7714
Zhang, YX,Zhang, YP,Li, DL,et al. Zinc distribution in mouse brain by SRXRF[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2006,269(1):235.
APA Zhang, YX.,Zhang, YP.,Li, DL.,Zhang, GL.,Long, JG.,...&Zhang, YX .(2006).Zinc distribution in mouse brain by SRXRF.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,269(1),235.
MLA Zhang, YX,et al."Zinc distribution in mouse brain by SRXRF".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 269.1(2006):235.
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