Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
Zinc distribution in mouse brain by SRXRF | |
Zhang, YX(张元勋); Zhang, YP(张勇平); Li, DL; Zhang, GL(张桂林); Long, JG(龙家丽); Shen, H; Huang, YY; He, W; Zhang, YX (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China | |
2006 | |
Source Publication | JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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ISSN | 0236-5731 |
Volume | 269Issue:1Pages:235 |
Abstract | In order to explore the interaction between the expression of ZnT3 (Zinc Transporter 3) mRNA (Messenger Ribonucleic Acid) and the concentration of elemental zinc in mouse brain, zinc distribution in brain was determined by synchrotron radiation X-ray fluorescence (SRXRF) technique and a ZnT3 mRNA expression in tissue was examined by the reverse-transcriptase polymerase chain reaction (RT-PCR) method.The results show that the zinc concentration is not evenly distributed in brain slices. Its concentrations in cerebral cortex and hippocampus are nearly 5-10 times higher than those in other positions. A corresponding relation is that ZnT3 mRNA in cerebral cortex, hippocampus and testis has higher abundant degree, but it is not examined out in other tissues. Furthermore, the results promote that ZnT3 facilitates the accumulation of zinc in synaptic vesicles and may play an important role in structuring of vesicular zinc pool. |
Subject Area | Physics |
Indexed By | SCI |
Language | 英语 |
Funding Project | 应物所项目组 |
WOS ID | WOS:000239298600036 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/8241 |
Collection | 中科院上海应用物理研究所2004-2010年 |
Corresponding Author | Zhang, YX (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China |
Recommended Citation GB/T 7714 | Zhang, YX,Zhang, YP,Li, DL,et al. Zinc distribution in mouse brain by SRXRF[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2006,269(1):235. |
APA | Zhang, YX.,Zhang, YP.,Li, DL.,Zhang, GL.,Long, JG.,...&Zhang, YX .(2006).Zinc distribution in mouse brain by SRXRF.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,269(1),235. |
MLA | Zhang, YX,et al."Zinc distribution in mouse brain by SRXRF".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 269.1(2006):235. |
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