CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Nanodissection of single- and double-stranded DNA by atomic force microscopy
An, HJ; Guo, YC; Zhang, XD; Zhang, Y(张益); Hu, J(胡钧); Hu, J (reprint author), Shanghai Jiao Tong Univ, Coll Life Sci & Biotechnol, Shanghai 200030, Peoples R China
2005
Source PublicationJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
ISSN1533-4880
Volume5Issue:10Pages:1656
AbstractNanodissection of single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) has been investigated by atomic force microscopy (AFM). It is found that both ss- and dsDNA can be repeatedly dissected by an AFM tip. However, a comparison study indicates that ssDNA is a little bit more easily broken by the AFM tip than dsDNA. This is supported by the fact that the time requested to break ssDNA is shorter than that of dsDNA in the same dissection procedure under the same load. Our experiment also shows that dissection of the DNA strand is very sensitive to the load applied, and a small change of the load lead to different results.
KeywordNanodissection Single-stranded Dna (ssDna) Double-stranded Dna (dsDna) Atomic Force Microscopy (Afm)
Subject AreaPhysics
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000232129900008
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8324
Collection中科院上海应用物理研究所2004-2010年
Corresponding AuthorHu, J (reprint author), Shanghai Jiao Tong Univ, Coll Life Sci & Biotechnol, Shanghai 200030, Peoples R China
Recommended Citation
GB/T 7714
An, HJ,Guo, YC,Zhang, XD,et al. Nanodissection of single- and double-stranded DNA by atomic force microscopy[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2005,5(10):1656.
APA An, HJ,Guo, YC,Zhang, XD,Zhang, Y,Hu, J,&Hu, J .(2005).Nanodissection of single- and double-stranded DNA by atomic force microscopy.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,5(10),1656.
MLA An, HJ,et al."Nanodissection of single- and double-stranded DNA by atomic force microscopy".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 5.10(2005):1656.
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