CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
羰基铼[~(188)Re]标记含RGD多肽
唐林; 于俊峰; 夏姣云; 尹端沚
2006
Source Publication同位素
Issue1
Abstract以fac-[188Re(CO)3(H2O)3]+为前体标记了2个含RGD的多肽:HGRGD(D)F(组氨酸-甘氨酸-精氨酸-甘氨酸-天冬氨酸-苯丙氨酸)和H CRGD(D)FC(组氨酸-半胱氨酸-精氨酸-甘氨酸-天冬氨酸-苯丙氨酸-半胱氨酸)。75℃反应30 min即得到了标记产物188Re-HGRGD(D)F和H CRGD(D)FC,标记率和放化纯度均>90%。体外稳定性实验结果表明,两个标记产物在小牛血清中稳定性都差于磷酸缓冲溶液;相比之下H CRGD(D)FC稳定性稍好于188Re-HGRGD(D)F。标记产物不会引起红细胞的溶血和凝聚现象,表明这两种标记物均可用作注射用药。
Keyword188re Fac-[188re(Co)3(H2o)3]+ Rgd 多肽
Indexed ByCNKI
Language中文
Funding Project应物所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8529
Collection中科院上海应用物理研究所2004-2010年
Corresponding Author唐林
Recommended Citation
GB/T 7714
唐林,于俊峰,夏姣云,等. 羰基铼[~(188)Re]标记含RGD多肽[J]. 同位素,2006(1).
APA 唐林,于俊峰,夏姣云,&尹端沚.(2006).羰基铼[~(188)Re]标记含RGD多肽.同位素(1).
MLA 唐林,et al."羰基铼[~(188)Re]标记含RGD多肽".同位素 .1(2006).
Files in This Item: Download All
File Name/Size DocType Version Access License
羰基铼[^188Re]标记含RGD多肽.(256KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[唐林]'s Articles
[于俊峰]'s Articles
[夏姣云]'s Articles
Baidu academic
Similar articles in Baidu academic
[唐林]'s Articles
[于俊峰]'s Articles
[夏姣云]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[唐林]'s Articles
[于俊峰]'s Articles
[夏姣云]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 羰基铼[^188Re]标记含RGD多肽.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.