CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Novel polyethylenimine nanogels as potential gene carriers produced via photochemistry in surfactant-free aqueous solution
Xu, DM(徐冬梅); Yu, JH; Liu, YB; Sun, HW; Xu, JY; Sheng, KL(盛康龙); Yao, SD(姚思德); Xu, YH; Lu, HL
2006
Conference Name2nd Asian Conference on Nanoscience and Nanotechnology
Source PublicationInternational Journal of Nanoscience, Vol 5, No 6
Pages753
Conference DateNOV 24-27, 2004
Conference PlaceBeijing, PEOPLES R CHINA
AbstractCationic polymer nanogels, positively-charged submicrometer polymeric particles that swell in water, have attracted an increasing research attentions in recent years because of their potential applications as gene carriers. In this paper, we report a novel method to synthesize polyethylenimine (PEI) nanogels with sizes ranging from 80 nm to 200 nm via UV irradiation at room temperature in aqueous solution without adding any kind of surfactants. The morphology of the nanoparticles is determined to be spherical. The nanogels are of high stability, high transfection efficiency, low toxicity and low inummogenicity, as having been confirmed by in vivo tests with mice as an animal model, and by in vitro tests with human lung and liver cancer cells as well.
Indexed BySCI
Funding Project应物所课题组
Language英语
Document Type会议论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8875
Collection中科院上海应用物理研究所2004-2010年
Recommended Citation
GB/T 7714
Xu, DM,Yu, JH,Liu, YB,et al. Novel polyethylenimine nanogels as potential gene carriers produced via photochemistry in surfactant-free aqueous solution[C],2006:753.
Files in This Item: Download All
File Name/Size DocType Version Access License
Novel polyethylenimi(203KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Xu, DM(徐冬梅)]'s Articles
[Yu, JH]'s Articles
[Liu, YB]'s Articles
Baidu academic
Similar articles in Baidu academic
[Xu, DM(徐冬梅)]'s Articles
[Yu, JH]'s Articles
[Liu, YB]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Xu, DM(徐冬梅)]'s Articles
[Yu, JH]'s Articles
[Liu, YB]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Novel polyethylenimine nanogels as potential gene carriers produced via photochemistry in surfactant-free aqueous solution.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.