CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Radiolabeling and in vitro evaluation of the polystyrene particles as a promising probe in biomedical sciences
Chen, JM; Tan, MG(谈明光); Zhang, GL(张桂林); Li, Y(李燕)
2007
Conference Name3rd Asia-Pacific Symposium Radichemistry
Source PublicationJOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
Pages387
Conference DateOCT 17-21, 2005
Conference PlaceBeijing, JAPAN
AbstractA simple direct labeling method was used to synthesize the iodinated ultrafine polystyrene particles. The assay of X-ray photoelectron spectroscopy (XPS) as well as Fourier-transform infrared (FT-IR) spectroscopy indicated the formation of stable covalent bond to aryl group of the polymer particles. The purified radioiodinated product was incubated with serum of rat, and then evaluated by in vitro stability test. The result showed that these synthesized ultrafine polystyrene particles were unmetabolized at 2 hours post-exposure, indicating the potential useful application of this labeled polymer particles as a promising probe in biomedical sciences.
ISSN0236-5731
Indexed BySCI
Funding Project应物所课题组
Language英语
Document Type会议论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/8885
Collection中科院上海应用物理研究所2004-2010年
Recommended Citation
GB/T 7714
Chen, JM,Tan, MG,Zhang, GL,et al. Radiolabeling and in vitro evaluation of the polystyrene particles as a promising probe in biomedical sciences[C],2007:387.
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