Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Radiolabeling and in vitro evaluation of the polystyrene particles as a promising probe in biomedical sciences | |
| Chen, JM; Tan, MG（谈明光）; Zhang, GL（张桂林）; Li, Y（李燕） | |
| 2007 | |
| Conference Name | 3rd Asia-Pacific Symposium Radichemistry |
| Source Publication | JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY |
| Pages | 387 |
| Conference Date | OCT 17-21, 2005 |
| Conference Place | Beijing, JAPAN |
| Abstract | A simple direct labeling method was used to synthesize the iodinated ultrafine polystyrene particles. The assay of X-ray photoelectron spectroscopy (XPS) as well as Fourier-transform infrared (FT-IR) spectroscopy indicated the formation of stable covalent bond to aryl group of the polymer particles. The purified radioiodinated product was incubated with serum of rat, and then evaluated by in vitro stability test. The result showed that these synthesized ultrafine polystyrene particles were unmetabolized at 2 hours post-exposure, indicating the potential useful application of this labeled polymer particles as a promising probe in biomedical sciences. |
| ISSN | 0236-5731 |
| Indexed By | SCI |
| Funding Project | 应物所课题组 |
| Language | 英语 |
| Document Type | 会议论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/8885 |
| Collection | 中科院上海应用物理研究所2004-2010年 |
| Recommended Citation GB/T 7714 | Chen, JM,Tan, MG,Zhang, GL,et al. Radiolabeling and in vitro evaluation of the polystyrene particles as a promising probe in biomedical sciences[C],2007:387. |
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