CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
蛋白质自由基损伤的保护和修复
朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德; 朱红平
2005-04-30
Source Publication辐射研究与辐射工艺学报
Issue02
Other AbstractReactive oxygen species (ROS) induce a lot of disease when the balance breaks between ROS and the enzymic and non-znzymic systems in human body to effectively scavenge ROS and prevent them from damaging the body. Proteins, which account for about 20% dry weight of a human cell, may be major target of attacks by ROS. It has been found that hydroxycinnamic acid, flavonoids and some other natural anti-oxidants can scavenge ROS inside body organs and tissues, and repair effectively oxidization damages to proteins. In recent years, stud- ies have been focused on mechanisms of the ROS caused damages to proteins, and on protecting proteins against ROS. In the meantime, explorations have been made on analyzing stable products of proteins involved in oxidation by ROS and on relationships between scavenging effects of natural anti-oxidants and their molecular structures. However, there are problems remaining before us for answers by still more investigations, such as what is the ROS attacking position on a protein macromolecule and how is the molecular modification of the ROS-attacked protein.
Keyword活性氧 抗氧化剂 蛋白
Indexed ByCNKI
Funding Project应物所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/9277
Collection中科院上海应用物理研究所2004-2010年
Corresponding Author朱红平
Recommended Citation
GB/T 7714
朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德,朱红平. 蛋白质自由基损伤的保护和修复[J]. 辐射研究与辐射工艺学报,2005(02).
APA 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德,&朱红平.(2005).蛋白质自由基损伤的保护和修复.辐射研究与辐射工艺学报(02).
MLA 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德,et al."蛋白质自由基损伤的保护和修复".辐射研究与辐射工艺学报 .02(2005).
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