CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
光化学法合成高基因转染效率的聚乙烯亚胺
徐冬梅,余家会,刘永彪,孙汉文,宫培军,洪军,姚思德; 徐冬梅
2005-04-30
Source Publication辐射研究与辐射工艺学报
Issue02
Other AbstractIn this paper, we report a novel method to synthesize polyethylenimine (PEI) nanogels in the range of 80— 200nm with narrow size distribution by photo-chemistry at room temperature in aqueous solution. The nanogels’ size, size distributions and zeta potential were determined by photo correlation spectroscopy (PCS). Spherical morphology of the nanogels was characterized by scanning electron microscopy (SEM) and confirmed by atomic force microscopy (AFM). The nanogels are of high stability, low toxicity and low immunogenicity, as having been confirmed in in vivo tests with mice as animal model, and in vitro tests with human lung and liver cancer cells as well. Efforts are being made for further studies on synthesis and applications of the nanogels.
Keyword聚乙烯亚胺 光化学 基因转染
Indexed ByCNKI
Funding Project应物所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/9301
Collection中科院上海应用物理研究所2004-2010年
Corresponding Author徐冬梅
Recommended Citation
GB/T 7714
徐冬梅,余家会,刘永彪,孙汉文,宫培军,洪军,姚思德,徐冬梅. 光化学法合成高基因转染效率的聚乙烯亚胺[J]. 辐射研究与辐射工艺学报,2005(02).
APA 徐冬梅,余家会,刘永彪,孙汉文,宫培军,洪军,姚思德,&徐冬梅.(2005).光化学法合成高基因转染效率的聚乙烯亚胺.辐射研究与辐射工艺学报(02).
MLA 徐冬梅,余家会,刘永彪,孙汉文,宫培军,洪军,姚思德,et al."光化学法合成高基因转染效率的聚乙烯亚胺".辐射研究与辐射工艺学报 .02(2005).
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