CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study
Tang, Ruizhi(唐睿智); Zhang, Peng(张鹏); Li, Haixia(李海霞); Liu, Yancheng; Wang, Wenfeng(王文峰)
2011
Source PublicationJOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
ISSN1011-1344
Volume105Issue:2Pages:157
AbstractThe photosensitized oxidation of guanine (G) by the triplet state of xanthone (XT) and the repair for photo-damaged G(-H)(center dot) by ferulic acid (FCA) were investigated using the laser flash photolysis technique. The rate constants of the reaction of triplet state of XT with G and with FCA were determined as 4.5 x 10(9) and 8.0 x 10(9) L mol(-1)s(-1), respectively. Laser exposure was performed on the N(2)-saturated acetonitrile/water (v/v, 1:1) solution containing G, XT and FCA. The transient absorption spectra indicated that the triplet state of XT first reacted with G predominantly to form the oxidized radical G(-H)(center dot). The radical G(-H)(center dot) was rapidly repaired by FCA, and the rate constant for the repair reaction was determined as 1.1 x 10(9) L mol(-1) s(-1). These results demonstrated that non-enzymatic repair is a feasible method for repairing photosensitized DNA bases oxidation. (C) 2011 Elsevier B.V. All rights reserved.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000296678600006
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/9564
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Tang, Ruizhi,Zhang, Peng,Li, Haixia,et al. Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2011,105(2):157.
APA Tang, Ruizhi,Zhang, Peng,Li, Haixia,Liu, Yancheng,&Wang, Wenfeng.(2011).Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,105(2),157.
MLA Tang, Ruizhi,et al."Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 105.2(2011):157.
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