Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Synthesis and Radio-labeling of 4-Substituted Cyclofenil | |
| Zhu Hua（朱华）; Lin Jianguo; Shen Yumei（沈玉梅） | |
| 2011 | |
| Source Publication | ACTA CHIMICA SINICA
 |
| ISSN | 0567-7351 |
| Volume | 69Issue:10Pages:1197 |
| Abstract | Starting from cyclofenil, a serial of cyclofenil-FEt derivatives were prepared. Generally speaking pentacyclofenil-FEt has greater relative binding affinity (RBA) to estradiol receptors than that of estradiol. The precursor compounds were synthesized for potential radioactive imaging agents, and their structures were characterized by ultraviolet, infrared, (1)H NMR, (19)F NMR, and ESI-HRMS techniques. The non-radioactive/radioactive compounds were synthesized. The study provides a useful assessment of the stage of the breast cancer by imaging ER beta with the PET (positron emission tomography) imaging. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000291898500009 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/9599 |
| Collection | 中科院上海应用物理研究所2011-2019年 |
| Recommended Citation GB/T 7714 | Zhu Hua,Lin Jianguo,Shen Yumei. Synthesis and Radio-labeling of 4-Substituted Cyclofenil[J]. ACTA CHIMICA SINICA,2011,69(10):1197. |
| APA | Zhu Hua,Lin Jianguo,&Shen Yumei.(2011).Synthesis and Radio-labeling of 4-Substituted Cyclofenil.ACTA CHIMICA SINICA,69(10),1197. |
| MLA | Zhu Hua,et al."Synthesis and Radio-labeling of 4-Substituted Cyclofenil".ACTA CHIMICA SINICA 69.10(2011):1197. |
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