CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Synthesis and Radio-labeling of 4-Substituted Cyclofenil
Zhu Hua(朱华); Lin Jianguo; Shen Yumei(沈玉梅)
2011
Source PublicationACTA CHIMICA SINICA
ISSN0567-7351
Volume69Issue:10Pages:1197
AbstractStarting from cyclofenil, a serial of cyclofenil-FEt derivatives were prepared. Generally speaking pentacyclofenil-FEt has greater relative binding affinity (RBA) to estradiol receptors than that of estradiol. The precursor compounds were synthesized for potential radioactive imaging agents, and their structures were characterized by ultraviolet, infrared, (1)H NMR, (19)F NMR, and ESI-HRMS techniques. The non-radioactive/radioactive compounds were synthesized. The study provides a useful assessment of the stage of the breast cancer by imaging ER beta with the PET (positron emission tomography) imaging.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000291898500009
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/9599
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Zhu Hua,Lin Jianguo,Shen Yumei. Synthesis and Radio-labeling of 4-Substituted Cyclofenil[J]. ACTA CHIMICA SINICA,2011,69(10):1197.
APA Zhu Hua,Lin Jianguo,&Shen Yumei.(2011).Synthesis and Radio-labeling of 4-Substituted Cyclofenil.ACTA CHIMICA SINICA,69(10),1197.
MLA Zhu Hua,et al."Synthesis and Radio-labeling of 4-Substituted Cyclofenil".ACTA CHIMICA SINICA 69.10(2011):1197.
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