CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecular Probe of Estrogen Receptor beta
Yang Guang(杨光); Zhu Hua(朱华); Shen Yumei(沈玉梅)
2011
Source PublicationCHINESE JOURNAL OF ORGANIC CHEMISTRY
ISSN0253-2786
Volume31Issue:5Pages:715
AbstractNew polyethylene glycol (PEG)-cyclofenil analogues based on its good affinity to estrogen receptor beta, containing tridentate ligand chelating system, were synthesized as molecular probe precursors for single-photon emission computed tomography (SPECT) imaging of breast cancer. The precursors were radiolabeled with (99m)Tc successfully. The key step in the process was the preparation of PEG-substituted cyclofenil and the reaction was clear with high yield (98%) and rapid reaction rate (completed within 30 min). Each step of the whole process was performed with relatively high yield under mild conditions. The exploration is extremely valuable for the radiolabeled experiment and micro-SPECT imaging study.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000291508800017
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/9600
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Yang Guang,Zhu Hua,Shen Yumei. Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecular Probe of Estrogen Receptor beta[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2011,31(5):715.
APA Yang Guang,Zhu Hua,&Shen Yumei.(2011).Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecular Probe of Estrogen Receptor beta.CHINESE JOURNAL OF ORGANIC CHEMISTRY,31(5),715.
MLA Yang Guang,et al."Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecular Probe of Estrogen Receptor beta".CHINESE JOURNAL OF ORGANIC CHEMISTRY 31.5(2011):715.
Files in This Item: Download All
File Name/Size DocType Version Access License
Synthesis of Novel P(1140KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yang Guang(杨光)]'s Articles
[Zhu Hua(朱华)]'s Articles
[Shen Yumei(沈玉梅)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yang Guang(杨光)]'s Articles
[Zhu Hua(朱华)]'s Articles
[Shen Yumei(沈玉梅)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yang Guang(杨光)]'s Articles
[Zhu Hua(朱华)]'s Articles
[Shen Yumei(沈玉梅)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecular Probe of Estrogen Receptor beta.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.