Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| DISTRIBUTION OF BROMO[METHYLENE-H-3]ACETAMIDE IN ONCOMELANIA SNAILS, CARPS, AND MICE | |
| WANG, GF; SONG, GM; WANG, GP（王国平）; ZHOU, MY（周美英）; ZHAO, XL（赵夏令）; BECKER, W | |
| 1991 | |
| Source Publication | ACTA PHARMACOLOGICA SINICA
 |
| ISSN | 0253-9756 |
| Volume | 12Issue:3Pages:232 |
| Abstract | Bromoacetamide show a high molluscicidal effect, low toxicity to fish and good solubility in water. It is a promising molluscicide. The present paper reported the distribution of bromo[methylene-H-3]acetamide in Oncomelania snails, carps, and mice. Radioactivity in animals was measured by liquid scintillation counting. In Oncomelania snails the radioactivity gradually increased with exposure time and drug concentration. The highest level was found in the head-foot, reaching 12.5 x 10(3) dpm . mg-1 after exposure to the drug for 24 h, whereas the levels in liver and other tissue were 3.0 x 10(3) and 3.8 x 10(3) dpm . mg-1 respectively. Carps absorbed bromo[methylene-H-3]acetamide similarly as in Oncomelania snails, but the levels in tissues were less than those in Oncomelania snails. Bromo[methylene-H-3]acetamide 0.5 ml (1.4-mu-mol . L-1) was given ig to mice. Blood samples of 3 mice were collected at 0.5, 1, 3, 6, 12, 24 and 96 h after ig. The peak levels was found within 12 h and then declined gradually. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:A1991FL66500011 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/9942 |
| Collection | 中科院上海原子核所2003年前 |
| Recommended Citation GB/T 7714 | WANG, GF,SONG, GM,WANG, GP,et al. DISTRIBUTION OF BROMO[METHYLENE-H-3]ACETAMIDE IN ONCOMELANIA SNAILS, CARPS, AND MICE[J]. ACTA PHARMACOLOGICA SINICA,1991,12(3):232. |
| APA | WANG, GF,SONG, GM,WANG, GP,ZHOU, MY,ZHAO, XL,&BECKER, W.(1991).DISTRIBUTION OF BROMO[METHYLENE-H-3]ACETAMIDE IN ONCOMELANIA SNAILS, CARPS, AND MICE.ACTA PHARMACOLOGICA SINICA,12(3),232. |
| MLA | WANG, GF,et al."DISTRIBUTION OF BROMO[METHYLENE-H-3]ACETAMIDE IN ONCOMELANIA SNAILS, CARPS, AND MICE".ACTA PHARMACOLOGICA SINICA 12.3(1991):232. |
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