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基于碎片方法的N-异噁唑-5-酰胺类HSP90抑制剂的发现 会议论文
第十二届全国青年药学工作者最新科研成果交流会论文集, 中国江苏南京
Authors:  陈丹琦;  沈爱军;  李健;  石峰;  Wuyan Chen;  任景;  黄敏;  刘红椿;  许叶春;  王昕;  陈奕;  杨敏;  何建华;  王月琴;  王丽萍;  耿美玉;  熊兵;  沈竞康
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Hsp90  抑制剂  基于碎片的药物发现  晶体学  
Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 11, 页码: 2525—2529
Authors:  Ren, J;  Li, J;  Wang, YQ;  Chen, WY;  Shen, AJ;  Liu, HC;  Chen, DQ;  Cao, DY;  Li, YL;  Zhang, NX;  Xu, YC;  Geng, MY;  He, JH;  Xiong, B;  Shen, JK;  mygeng@simm.ac.cn;  hejh@sinap.ac.cn;  bxiong@simm.ac.cn
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Shock-protein 90  Drug Discovery  Chaperone  Ligand  Heat-shock-protein-90  Design