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谷胱甘肽的宽频太赫兹光谱研究 期刊论文
分析化学, 2020, 卷号: 48, 期号: 10, 页码: 1367-1374
Authors:  郭聪;  朱中杰;  沈建雄;  张宗昌;  张建兵;  赵德明;  赵红卫
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宽频太赫兹光谱  还原型谷胱甘肽  氧化型谷胱甘肽  低频振动  氢键  
Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 卷号: 13, 期号: 5, 页码: 1531—1535
Authors:  Ren, J;  Yang, M;  Liu, HC;  Cao, DY;  Chen, DQ;  Li, J;  Tang, L;  He, JH;  Chen, YL;  Geng, MY;  Xiong, B;  Shen, JK
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Heat-shock Proteins  3-component Condensation  Discovery  Heat-shock-protein-90  Identification  Pyrazines  Potent  Chaperone  
基于碎片方法的N-异噁唑-5-酰胺类HSP90抑制剂的发现 会议论文
第十二届全国青年药学工作者最新科研成果交流会论文集, 中国江苏南京
Authors:  陈丹琦;  沈爱军;  李健;  石峰;  Wuyan Chen;  任景;  黄敏;  刘红椿;  许叶春;  王昕;  陈奕;  杨敏;  何建华;  王月琴;  王丽萍;  耿美玉;  熊兵;  沈竞康
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Hsp90  抑制剂  基于碎片的药物发现  晶体学  
Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 11, 页码: 2525—2529
Authors:  Ren, J;  Li, J;  Wang, YQ;  Chen, WY;  Shen, AJ;  Liu, HC;  Chen, DQ;  Cao, DY;  Li, YL;  Zhang, NX;  Xu, YC;  Geng, MY;  He, JH;  Xiong, B;  Shen, JK;  mygeng@simm.ac.cn;  hejh@sinap.ac.cn;  bxiong@simm.ac.cn
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Shock-protein 90  Drug Discovery  Chaperone  Ligand  Heat-shock-protein-90  Design  
基于片段的药物发现方法进展 期刊论文
药学学报, 2013, 期号: 1, 页码: 14-24
Authors:  任景;  李健;  石峰;  王昕;  何建华;  许叶春;  张乃霞;  熊兵;  沈竞康
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片段  筛选  优化  药物发现  
Discovery of pyrazole as C-terminus of selective BACE1 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 68, 页码: CONCATENATE(Sheet1!I89,-Sheet1!J89)
Authors:  Zou, Yiquan;  Xu, Lei;  Chen, Wuyan;  Zhu, Yiping;  Chen, Tiantian;  Fu, Yan;  Li, Li;  Ma, Lanping;  Xiong, Bing;  Wang, Xin;  Li, Jian;  He, Jianhua;  Zhang, Haiyan;  Xu, Yechun;  Li, Jia;  Shen, Jingkang
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Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 10, 页码: CONCATENATE(Sheet1!I134,-Sheet1!J134)
Authors:  Zhao, Lele;  Cao, Danyan;  Chen, Tiantian;  Wang, Yingqing;  Miao, Zehong;  Xu, Yechun;  Chen, Wuyan;  Wang, Xin;  Li, Yardian;  Du, Zhiyan;  Xiong, Bing;  Li, Jian;  Xu, Chunyan(徐春艳);  Zhang, Naixia;  He, Jianhua(何建华);  Shen, Jingkang
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基于片段的热休克蛋白90(HSP90)抑制剂研究 会议论文
2012长三角药物化学研讨会论文集, 2012
Authors:  任景;  李健;  陈五妍;  何建华;  熊兵;  许叶春;  沈竞康
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片段:6825  Hsp90:5460  热休克蛋白:4822  抑制剂:582  结合位点:75  分子伴侣:17  治疗靶点:12  细胞周期调控:10  药物发现:10  信号转导:7  细胞质:2  凋亡:1  路径:0  Atp:0  
恒流模式直流流强检测系统的优化 期刊论文
核技术, 2012, 期号: 2, 页码: 81-86
Authors:  熊云;  阎映炳;  冷用斌;  易星;  赖龙伟;  王宝鹏;  张宁;  陈之初
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用(γ,n)反应生产放射性药物~(123)I的研究 期刊论文
核技术, 2000, 期号: 08
Authors:  裴元吉;  刘清亮;  李裕熊;  陈文明;  许柄;  罗雪芳;  孙葆根;  汪勇先;  盛树刚;  张新华;  曹本红;  王高栋
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